June 20, 2024Our paper entitled “A Systematically Optimized Miniaturized Mesoscope (SOMM) for large-scale calcium imaging in freely moving mice” has been published…
April 4, 2024Our paper entitled “Simultaneous, cortex-wide and cellular-resolution neuronal population dynamics reveal an unbounded scaling of dimensionality with neuron number” has…
February 24, 2023Our paper entitled “Mesoscale volumetric light field (MesoLF) imaging of neuroactivity across cortical areas at 18 Hz” has been published…
August 30, 2021Our paper entitled “High-Speed, Cortex-Wide Volumetric Recording of Neuroactivity at Cellular Resolution using Light Beads Microscopy” has been published in…- January 16, 2020Our paper entitled “Cerebellar neurodynamics predict decision timing and outcome on single-trial level” has been published in Cell. Decision making…
- April 10, 2019Our paper entitled “Volumetric Ca2+ Imaging in the Mouse Brain using Hybrid Multiplexed Sculpted Light (HyMS) Microscopy” has been published…
- May 7, 2018Our paper entitled “High-speed volumetric imaging of neuronal activity in freely moving rodents” has been published in Nature Methods. We…
March 29, 2018Our paper entitled "Brain-wide 3D light-field imaging of neuronal activity with speckle-enhanced resolution" has been published in Optica. A major…- June 26, 2017Our paper entitled “Video rate volumetric Ca2+ imaging across cortical layers using Seeded Iterative Demixing (SID) microscopy” has been published…
October 31, 2016Our paper entitled “Fast volumetric calcium imaging across multiple cortical layers using sculpted light” has been published in Nature Methods.…- October 11, 2016Our paper entitled “A force-induced directional switch of a molecular motor enables parallel microtubule bundle formation” has been published in…
- July 19, 2016Our paper entitled “Direct detection of a single photon by humans” has been published in Nature Communications. As early as…
- January 15, 2015We have developed strategies for optimizing of the present tradeoffs in light-sculpting microscopy by evaluating various scanning modalities theoretically and…
May 18, 2014Our paper entitled “Simultaneous Whole-Brain Functional Imaging of Neuronal Activity using Light-Field Microscopy” has been published in Nature Methods. High-speed,…- September 9, 2013Wide-field temporal focusing (WF-TEFO) is a two-photon imaging technique which is based on light-sculpting. It effectively decouples the parameters governing…
- August 26, 2013Most of our today’s understanding on the function of channels is based on static crystallography data and electrophysiology. However, it…
- March 24, 2013The need for optical sectioning in bio-imaging has amongst others led to the development of the two-photon scanning microscopy. However,…
- February 22, 2013Optical trapping is a single molecule technique that allows to study mechanical properties of single polymer molecules, proteins, or individual…
October 24, 2011Photoactivated Localization Microscopy (PALM) is one of the recently emerging techniques for optical imaging of protein distributions in biological samples…- October 24, 2011It is widely accepted that that the patterns of action potentials in neuronal circuits underlie cognitive functions such as perception,…
