Category: Research
Molecular mechanism underlying parallel microtubule bundle formation
October 11, 2016
Our paper entitled “A force-induced directional switch of a molecular motor enables parallel microtubule bundle formation” has been published in…Direct detection of a single photon by humans
July 19, 2016
Our paper entitled “Direct detection of a single photon by humans” has been published in Nature Communications. As early as…Hybrid light-sculpting-scanning for versatile high-speed calcium imaging
January 15, 2015
We have developed strategies for optimizing of the present tradeoffs in light-sculpting microscopy by evaluating various scanning modalities theoretically and…Simultaneous whole-brain functional imaging of neuronal activity using Light-Field Microscopy
May 18, 2014
Our paper entitled “Simultaneous Whole-Brain Functional Imaging of Neuronal Activity using Light-Field Microscopy” has been published in Nature Methods. High-speed,…High-speed brain-wide 3D calcium imaging of neuronal activity with sculpted light
September 9, 2013
Wide-field temporal focusing (WF-TEFO) is a two-photon imaging technique which is based on light-sculpting. It effectively decouples the parameters governing…IR-spectroscopy of KcsA binding states
August 26, 2013
Most of our today’s understanding on the function of channels is based on static crystallography data and electrophysiology. However, it…Ultrafast widefield optical sectioning microscopy
March 24, 2013
The need for optical sectioning in bio-imaging has amongst others led to the development of the two-photon scanning microscopy. However,…Optical force spectroscopy
February 22, 2013
Optical trapping is a single molecule technique that allows to study mechanical properties of single polymer molecules, proteins, or individual…Multilayer three-dimensional super-resolution microscopy
October 24, 2011
Photoactivated Localization Microscopy (PALM) is one of the recently emerging techniques for optical imaging of protein distributions in biological samples…Single-neuron-specific optogenetic control
October 24, 2011
It is widely accepted that that the patterns of action potentials in neuronal circuits underlie cognitive functions such as perception,…