New Article on bioRxiv: Simultaneous, cortex-wide and cellular-resolution neuronal population dynamics reveal an unbounded scaling of dimensionality with neuron number

New Article on bioRxiv: Simultaneous, cortex-wide and cellular-resolution neuronal population dynamics reveal an unbounded scaling of dimensionality with neuron number

News, Publications
We are happy to announce that a new manuscript entitled “Simultaneous, cortex-wide and cellular-resolution neuronal population dynamics reveal an unbounded scaling of dimensionality with neuron number” has been uploaded to the bioRxiv preprint server. The brain’s remarkable properties arise from collective activity of millions of neurons.Widespread application of dimensionality reduction to multi-neuron recordings implies thatneural dynamics can be approximated by low-dimensional “latent” signals reflecting neuralcomputations. However, what would be the biological utility of such a redundant andmetabolically costly encoding scheme and what is the appropriate resolution and scale of neuralrecording to understand brain function? Imaging the activity of one million neurons at cellularresolution and near-simultaneously across mouse cortex, we demonstrate an unbounded scalingof dimensionality with neuron number. While half of the neural variance lies within sixteenbehavior-related dimensions, we find this…
Read More