New publication in Nature Methods
Our paper entitled “Fast volumetric calcium imaging across multiple cortical layers using sculpted light” has been published in Nature Methods. In this work, we present a (more…)
New publication in Cell
Our paper entitled "A force-induced directional switch of a molecular motor enables parallel microtubule bundle formation" by Maxim I. Molodtsov et al. has been published in Cell. Microtubule-organizing centers (MTOCs) nucleate microtubules that can grow autonomously in any direction. To generate bundles of parallel microtubules originating from a single MTOC, the growth of multiple microtubules needs to coordinated, but the underlying mechanism is unknown. Here, we show that a conserved two-component system consisting of the plus-endtracker EB1 and the minus-end-directed molecular motor Kinesin-14 is sufficient to promote parallel microtubule growth. The underlying mechanism relies on the ability of Kinesin-14 to guide growing plus ends along existing microtubules. The generality of this finding is supported by yeast, Drosophila, and human EB1/Kinesin-14 pairs. We demonstrate that plus-end guiding involves a directional switch…
New publication in Nature Communications
Our paper entitled “Direct Detection of a Single Photon by Humans” by Tinsley J. N. et. al., has been published in Nature Communications. In this study we have shown that humans are capable of detecting a single photon onto their eyes with a probability above chance. This was done by developing a quantum light source based on spontaneous parametric down-conversion (SPDC) which can generate single-photon states of light and combining it with a state-of-the-art psychophysics procedure. Thereby we could show that the human visual system including the post-processing performed by the retina and the brain can detect a single photon incident onto the eye. Read the publication or a short summary. Please have also a look at the Nature News article by Davide Castelvecchi as well as the articles on…